Testing multiple biological mediators simultaneously
نویسندگان
چکیده
منابع مشابه
Testing multiple biological mediators simultaneously
MOTIVATION Modern biomedical and epidemiological studies often measure hundreds or thousands of biomarkers, such as gene expression or metabolite levels. Although there is an extensive statistical literature on adjusting for 'multiple comparisons' when testing whether these biomarkers are directly associated with a disease, testing whether they are biological mediators between a known risk fact...
متن کاملAppendix and Supplementary Material for Testing multiple biological mediators simultaneously: Controlling FWER and FDR
Joshua N. Sampson, Simina M. Boca, Steven C. Moore, and Ruth Heller Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, US, [email protected] Innovation Center for Biomedical Informatics, Georgetown University, Washington, DC, US, [email protected] Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, US, steven.moor...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btt633